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Flexeril - Cyclobenzeprine

By , About.com Guide

Updated January 30, 2006

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Brand Name :
Flexeril. By prescription only.
Generic Name:
Cyclobenzeprine. Cyclobenzeprine is available in generic form, by prescription only.
Class and Drug Action:
Skeletal Muscle Relaxant. Cyclobenzeprine works on local muscles to relieve spasm. It is not effective for conditions involving the nervous system, such as multiple sclerosis. Cyclobenzeprine is used short-term, in conjunction with physical therapy and rest for acute cases of muscle injury, for example sprains and strains.
Appropriate Usage:
Duration should be between 2-3 weeks. Cyclobenzeprine is taken by mouth up to 3 times per day, unless otherwise prescribed by your doctor. DO NOT INCREASE YOUR DOSAGE! If you miss a dose, and it is now closer the time of the next dose, just resume taking the medication with the next scheduled time. Do not double dose to make up for a missed dosage.
Storage:
Store cyclobenzeprine at 77 degress F (25 degrees C). For short periods of time storing cyclobenzeprine at room temprature (41 - 86 degrees F) is acceptable. Don't store cyclobenzeprine in the bathroom!
Side Effects:
The most common side effects include:
  • dry mouth
  • drowsiness
  • dizziness
  • tiredness
  • constipation
  • blurred vision
  • unplesant taste
  • nervousness
  • confusion
  • abdominal pain or discomfort
More Serious Side Effects:
Serious side effects are rare, but if these do occur they require prompt medical attention 2:
  • mental and mood changes, for example hallucinations and confusion
  • difficulty in urinating
  • dark urine
  • fast, pounding and/or irregular heartbeat
  • fainting
  • yellowing of the eyes and/or skin
  • stomach and/or abdominal pain
  • persistant nausea, vomiting and/or lack of appetite
  • seizures
  • loss of coordination
Precautions:
The elderly will be more sensitive to the side effects associated with this disease. Pregnant women should use only when absolutely necessary; the drug might pass on to the breast milk.

Because side effects include dizziness and drowsiness, exercise caution when deciding to drive a car or operate machinery. Alcohol will amplify these side effects, and is best limited, to prevent injury or accident.
More Precautions - Drug Interactions:
Careful! MAO inhibitors may cause serious, or even fatal results when interacting with cyclobenzeprine. See the next section for details.
Communicating with your Doctor is VERY IMPORTANT:
Always communicate the following with your doctor:
  • allergies, especially to Flexeril
  • overactive thyroid
  • arrhythmia
  • any other heart problems including congestive heart failure, heart block or conduction disorders
  • recent heart attack
  • liver disease
  • urinary retention
  • glaucoma
  • MAO inhibitors (see the list below).
IMPORTANT! If you take MAO inhibitors:
Stop taking the following drugs 2 weeks before taking cyclobenzeprine. Don't resume taking them until you have stopped the cyclobenzeprine for 2 weeks:
  • furazolidone
  • isocarboxazid
  • linezolid
  • moclobemide
  • phenelzine
  • procarbazine
  • selegiline[/il]
  • tranylcypromine
Certain types of other medications (asthma, weight loss, stimulants, drugs that cause drowsiness and tricyclic antidepressants, to name a few) may cause drug interaction problems. Tell your doctor EVERYTHING you are taking! For more information use the Drug Finder.


Bibliography
1 Cyclobenzeprine Oral. Rx Patient Drug Information from First DataBank 6.8.05. Rx List, The Internet Drug Index. Retrieved from: http://www.rxlist.com/drugs/drug-11372-Flexeril+Oral.aspx?drugid=11372&drugname=Flexeril+Oral January 30, 2006.

2 MedicineNet. 5.11.98. Retrieved from: http://www.medicinenet.com/cyclobenzaprine/article.htm January 30, 2006.

3. Malanga, Gerard, MD. Muscle Relaxants in the Treatment of Acute Low Back Pain, Types of Muscle Relaxing Medication: Part 4. Spine Universe. Retrieved from: http://www.spineuniverse.com/displayarticle.php/article1833.html. January 29, 2006.


Date Created: January 30, 2006.
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